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Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 21 102.77 74.17 20,061,443
Mutual Fund 6 8.79 6.93 1,875,083
Insider -- -- -- --

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 9 21.59 13.84 3,743,045
Sellers 6 -0.22 0.15 -40,616
Net -- 21.37 13.69 3,702,429

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 102.77 74.17 20,061,443
Top 10 Inst. 101.50 73.29 19,824,460
Top 20 Inst. 102.77 74.17 20,061,218
Top 50 Inst. 102.77 74.17 20,061,443

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 2 0.61 0.36 96,678
Core Growth 2 0.61 0.36 96,678
Income 1 0.23 0.16 42,576
Income Value 1 0.23 0.16 42,576
Index 2 1.13 0.78 210,329
Other 7 6.78 4.69 1,267,401
Broker Dealer 2 0.30 0.21 55,823
Hedge Fund 5 6.48 4.48 1,211,578
Value 2 19.88 13.74 3,715,702
Core Value 2 19.88 13.74 3,715,702

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
Clal Biotechnology Industries Ltd. 9,389,555 34.71 -400,000 12/31/16
Wellington Management Company, LLP 3,689,402 13.64 1,541,863 9/30/17
Migdal Insurance & Financial Holdings Ltd. 2,220,972 8.21 192,860 9/30/17
Rosenberg (Lior) 1,850,572 6.84 -- 2/15/17
Yelin Lapidot Holdings Ltd. 1,252,381 4.63 1,252,381 3/21/17
Broadfin Capital, L.L.C. 500,000 1.85 325,335 9/30/17
Alyeska Investment Group, L.P. 400,000 1.48 400,000 9/30/17
Baker Bros. Advisors LP 226,000 0.84 -- 9/30/17
California Public Employees' Retirement System 199,900 0.74 -- 9/30/17
Cavanal Hill Investment Management, Inc. 95,678 0.35 -- 8/31/17
Renaissance Technologies LLC 85,100 0.31 5,000 9/30/17
Wells Fargo Advisors 54,823 0.20 -10,940 9/30/17
Bank of Oklahoma, N.A. 42,576 0.16 23,306 9/30/17
Oppenheimer Asset Management Inc. 26,300 0.10 1,800 9/30/17
Harel Insurance Investments and Financial Services Ltd. 14,552 0.05 -- 9/30/17
Geode Capital Management, L.L.C. 10,429 0.04 -- 9/30/17
Morgan Stanley Wealth Management 1,000 -- -- 9/30/17
Bank of America Merrill Lynch (US) 1,000 -- -- 9/30/17
Lee Financial Corp 500 -- 500 9/30/17
Tower Research Capital LLC 478 -- -1,989 9/30/17
UBS Financial Services, Inc. 225 -- -1,280 9/30/17