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Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 25 95.75 79.54 21,512,651
Mutual Fund 7 7.28 6.78 1,835,081
Insider -- -- -- --

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 13 6.89 5.72 1,547,049
Sellers 4 -0.87 0.72 -195,841
Net -- 6.02 5.00 1,351,208

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 95.75 79.54 21,512,651
Top 10 Inst. 92.55 76.90 20,798,758
Top 20 Inst. 95.73 79.52 21,508,188
Top 50 Inst. 95.75 79.54 21,512,651

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 2 0.56 0.45 120,804
Core Growth 2 0.56 0.45 120,804
Income 1 0.20 0.16 44,012
Income Value 1 0.20 0.16 44,012
Index 3 1.04 0.86 232,964
Other 9 5.37 4.47 1,207,790
Broker Dealer 2 0.45 0.38 102,189
Hedge Fund 7 4.92 4.09 1,105,601
Value 2 16.37 13.60 3,678,479
Core Value 2 16.37 13.60 3,678,479

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
Clal Biotechnology Industries Ltd. 9,429,555 34.86 40,000 12/31/17
Wellington Management Company, LLP 3,642,979 13.47 -46,423 12/31/17
Migdal Insurance & Financial Holdings Ltd. 2,209,368 8.17 -11,604 12/31/17
Rosenberg (Lior) 1,850,572 6.84 -- 12/31/17
Yelin Lapidot Holdings Ltd. 1,432,381 5.30 180,000 12/31/17
Harel Insurance Investments and Financial Services Ltd. 754,434 2.79 739,882 12/31/17
Broadfin Capital, L.L.C. 500,000 1.85 -- 12/31/17
Meitav Dash Investments Ltd. 490,783 1.81 490,783 12/31/17
Alyeska Investment Group, L.P. 262,686 0.97 -137,314 12/31/17
Baker Bros. Advisors LP 226,000 0.84 -- 12/31/17
California Public Employees' Retirement System 199,900 0.74 -- 12/31/17
Cavanal Hill Investment Management, Inc. 119,804 0.44 24,126 11/30/17
Wells Fargo Advisors 101,189 0.37 46,366 12/31/17
Renaissance Technologies LLC 100,600 0.37 15,500 12/31/17
Delek Group, Ltd. 60,000 0.22 60,000 12/31/17
Bank of Oklahoma, N.A. 44,012 0.16 1,436 12/31/17
Oppenheimer Asset Management Inc. 35,500 0.13 9,200 12/31/17
ETF Managers Group, LLC 22,635 0.08 22,635 12/31/17
Citadel LLC 15,361 0.06 15,361 12/31/17
Geode Capital Management, L.L.C. 10,429 0.04 -- 12/31/17
UBS Financial Services, Inc. 1,509 0.01 1,284 12/31/17
Morgan Stanley Wealth Management 1,000 -- -- 12/31/17
Bank of America Merrill Lynch (US) 1,000 -- -- 12/31/17