United States securities and exchange commission logo May 31, 2022 Sharon Malka Chief Executive Officer MediWound Ltd. 42 Hayarkon Street Yavne 8122745, Israel Re: MediWound Ltd. Registration Statement on Form F-3 Filed May 25, 2022 File No. 333-265203 Dear Ms. Malka: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Michael Davis at 202-551-4385 or Joe McCann at 202-551-6262 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Michael Rosenberg